by Joseph E. Alouf, The Comprehensive Sourcebook Of Bacterial Protein Toxins Books available in PDF, EPUB, Mobi Format. Download The Comprehensive Sourcebook Of Bacterial Protein Toxins books, This book describes the major achievements and discoveries relevant to bacterial protein toxins since the turn of the new century illustrated by the discovery of more than fifty novel toxins (many of them identified through genome screening). The establishment of the three-dimensional crystal structure of more than 20 toxins during the same period offers deeper knowledge of structure-activity relationships and provides a framework to understand how toxins recognize receptors, penetrate membranes and interact with and modify intracellular substrates. Edited by two of the most highly regarded experts in the field from the Institut Pasteur, France 14 brand new chapters dedicated to coverage of historical and general aspects of toxinology Includes the major toxins of both basic and clinical interest are described in depth Details applied aspects of toxins such as therapy, vaccinology, and toolkits in cell biology Evolutionary and functional aspects of bacterial toxins evaluated and summarized Toxin applications in cell biology presented Therapy (cancer therapy, dystonias) discussed Vaccines (native and genetically engineered vaccines) featured Toxins discussed as biological weapons, comprising chapters on anthrax, diphtheria, ricin etc.
by John H. Freer, The Comprehensive Sourcebook Of Bacterial Protein Toxins Books available in PDF, EPUB, Mobi Format. Download The Comprehensive Sourcebook Of Bacterial Protein Toxins books, The Comprehensive Sourcebook of Bacterial Protein Toxins, Second Edition, provides an up-to-date description of the great advances made in our understanding of the structure, genetics, cellular, and molecular mechanisms of action of bacterial protein toxins over the past decade. This work follows and expands on the first edition (published in 1991), with 70% totally new content and full-color illustrations. Molecular biology, microbiology, immunology, cell biology, protein engineering, structural biochemistry, and clinical research in infectious diseases are brought together to provide a complete overview of the field. Key Features * Most up-to-date and comprehensive reference on the subject * Addresses recent achievements in basic and applied toxin research * Covers use of bacterial toxins in the development of new vaccines, immunodulators, and therapeutics against cancer and various neurological disorders * Written by internationally recognized scientists, including Randall Holmes, a recent candidate for presidency of the American Society for Microbiology
by Joseph E. Alouf, Sourcebook Of Bacterial Protein Toxins Books available in PDF, EPUB, Mobi Format. Download Sourcebook Of Bacterial Protein Toxins books, Written by an international team of leading scientists, this volume draws together a wealth of information on the structure, regulation, and activity of bacterial protein toxins. A comprehensive sourcebook on bacterial toxins, Sourcebook of Bacterial Protein Toxins is the first book designed to draw together current knowledge on these toxins. The 22 chapters of this book have been written by 44 internationally known specialists who have significantly contributed to the progress in the domains covered. This book will appeal to a wide readership, including microbiologists, biochemists, cell biologists, and physicians. It will also arouse the interest of students and scientists in other disciplines who see the power of these fascinating biological agents, either as exquisitely specific probes of cellular processes or as extremely potent agents of infectious disease.
by Zygmunt F. Dembek, Medical Aspects Of Biological Warfare Books available in PDF, EPUB, Mobi Format. Download Medical Aspects Of Biological Warfare books, Reflecting the critical threat posed by biological warfare and terrorism in a post 9-11 world, Medical Aspects of Biological Warfare (an update of Medical Aspects of Chemical and Biological Warfare published in 1997) addresses the weaponization of biological agents, categorizing potential agents as food, waterborne, or agricultural agents or toxins, and discusses their respective epidemiology. Recent advances in biomedical knowledge are presented that include descriptions of individual agents and the illnesses induced. Authors discuss biotoxins and explain methods for early identification for anthrax, plague, smallpox, alphaviruses, and staphylococcal enterotoxins. Case studies and research on successful management practices, treatments, and antidotes are also included.
by Mitchell F. Brin, Scientific And Therapeutic Aspects Of Botulinum Toxic Books available in PDF, EPUB, Mobi Format. Download Scientific And Therapeutic Aspects Of Botulinum Toxic books, Written by an international group of noted basic scientists and clinicians, this volume presents state-of-the-art information on the mechanisms of action, pharmacology, neurophysiological effects, and therapeutic uses of botulinum neurotoxins. A major portion of the book reviews recent clinical experience and clinical trials with botulinum toxin therapy for strabismus, dystonia, juvenile cerebral palsy, spasticity, hyperhidrosis, gastrointestinal and genitourinary disorders, headache, cosmetic facial conditions, and various disorders involving excessive muscle contraction or pain. Other chapters examine the immunology of botulinum toxins, the use of other chemodenervating agents, and the development of novel neurotoxin constructs.
by Martin J. Blaser, Infections Of The Gastrointestinal Tract Books available in PDF, EPUB, Mobi Format. Download Infections Of The Gastrointestinal Tract books, This updated second edition examines the gastrointestinal tract in relation to both immunocompetent and immunocompromised hosts. Written by specialists in infectious diseases and gastroenterology, this edition features discussion on the many infections of the gastrointestinal tract faced by adult and pediatric populations. The text traces the historical and epidemiological aspects of these disorders and provides detailed discussions on diagnosis, treatment, prevention and control, and should be of interest to the infectious disease specialist, gastroenterologist, primary care provider, internist, paediatrician and surgeon.